Cargando…
Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia
BACKGROUND: Haemoglobin S (HbS) is the gene known to confer the strongest advantage against malaria morbidity and mortality. Multiple HbS effects have been described resulting in protection against parasitaemia and reduction of severe malaria risk. This study aimed to explore HbS protection against...
Autores principales: | do Sambo, Maria Rosário, Penha-Gonçalves, Carlos, Trovoada, Maria Jesus, Costa, João, Lardoeyt, Roberto, Coutinho, António |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596417/ https://www.ncbi.nlm.nih.gov/pubmed/26445879 http://dx.doi.org/10.1186/s12936-015-0920-z |
Ejemplares similares
-
Risk factors for Plasmodium falciparum hyperparasitaemia in malarious children
por: Sowunmi, Akintunde, et al.
Publicado: (2011) -
Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia
por: Kyriacou, Helen M., et al.
Publicado: (2006) -
Hyperparasitaemia during clinical malaria episodes in infants aged 0–24 months and its association with in utero exposure to Plasmodium falciparum
por: Sylvester, Boniphace, et al.
Publicado: (2018) -
Hyperparasitaemia during bouts of malaria in French Guiana
por: Carme, Bernard, et al.
Publicado: (2013) -
Transforming Growth Factor Beta 2 and Heme Oxygenase 1 Genes Are Risk Factors for the Cerebral Malaria Syndrome in Angolan Children
por: Sambo, Maria Rosário, et al.
Publicado: (2010)