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Tissue Inhibitor of Metalloproteinase-2 Suppresses Collagen Synthesis in Cultured Keloid Fibroblasts

BACKGROUND: Keloids are defined as a kind of dermal fibroproliferative disorder resulting from the accumulation of collagen. In the remodeling of extracellular matrix, the balance between matrix metalloproteinases (MMPs) and the tissue inhibitors of metalloproteinases (TIMPs) is as critical as the p...

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Detalles Bibliográficos
Autores principales: Dohi, Teruyuki, Miyake, Koichi, Aoki, Masayo, Ogawa, Rei, Akaishi, Satoshi, Shimada, Takashi, Okada, Takashi, Hyakusoku, Hiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596445/
https://www.ncbi.nlm.nih.gov/pubmed/26495233
http://dx.doi.org/10.1097/GOX.0000000000000503