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The kdr-bearing haplotype and susceptibility to Plasmodium falciparum in Anopheles gambiae: genetic correlation and functional testing

BACKGROUND: Members of the Anophelesgambiae species complex are primary vectors of human malaria in Africa. It is known that a large haplotype shared between An. gambiae and Anophelescoluzzii by introgression carries point mutations of the voltage-gated sodium channel gene para, including the L1014F...

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Detalles Bibliográficos
Autores principales: Mitri, Christian, Markianos, Kyriacos, Guelbeogo, Wamdaogo M., Bischoff, Emmanuel, Gneme, Awa, Eiglmeier, Karin, Holm, Inge, Sagnon, N’Fale, Vernick, Kenneth D., Riehle, Michelle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596459/
https://www.ncbi.nlm.nih.gov/pubmed/26445487
http://dx.doi.org/10.1186/s12936-015-0924-8