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Randomized, Controlled, Thorough QT/QTc Study Shows Absence of QT Prolongation with Luseogliflozin in Healthy Japanese Subjects

Luseogliflozin is a selective sodium glucose co-transporter 2 (SGLT2) inhibitor. To evaluate the cardiac safety of luseogliflozin, a thorough QT/QTc study was conducted in healthy Japanese subjects. The effects of moxifloxacin on QT prolongation in Japanese subjects were also evaluated. In this doub...

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Detalles Bibliográficos
Autores principales: Kumagai, Yuji, Hasunuma, Tomoko, Sakai, Soichi, Ochiai, Hidekazu, Samukawa, Yoshishige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596473/
https://www.ncbi.nlm.nih.gov/pubmed/26444986
http://dx.doi.org/10.1371/journal.pone.0139873