Accurate interrogation of FCGR3A rs396991 in European and Asian populations using a widely available TaqMan genotyping method

A polymorphism in the receptor for the Fc region of IgG, Fc γ-receptor IIIa (FcγRIIIa, FCGR3A rs396991), has been inconsistently shown in the literature to have an effect on response to monoclonal antibody therapy in several indications. The rs396991 (T/G) polymorphism leads to an F176V substitution...

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Detalles Bibliográficos
Autores principales: Murphy, Kay E., Niederer, Heather A., King, Karen S., Harris, Elizabeth C., Glass, Sarah M., Cox, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596484/
https://www.ncbi.nlm.nih.gov/pubmed/26367501
http://dx.doi.org/10.1097/FPC.0000000000000175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596484/
https://www.ncbi.nlm.nih.gov/pubmed/26367501
http://dx.doi.org/10.1097/FPC.0000000000000175

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