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Accurate interrogation of FCGR3A rs396991 in European and Asian populations using a widely available TaqMan genotyping method
A polymorphism in the receptor for the Fc region of IgG, Fc γ-receptor IIIa (FcγRIIIa, FCGR3A rs396991), has been inconsistently shown in the literature to have an effect on response to monoclonal antibody therapy in several indications. The rs396991 (T/G) polymorphism leads to an F176V substitution...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Lippincott Williams & Wilkins
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596484/ https://www.ncbi.nlm.nih.gov/pubmed/26367501 http://dx.doi.org/10.1097/FPC.0000000000000175 |