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Pharmacodynamics of nine generic products of amikacin compared with the innovator in the neutropenic mouse thigh infection model

BACKGROUND: Previously, we validated the mouse thigh infection model to test the therapeutic equivalence of generic antibiotic products. Here, our aim was to compare the in vivo efficacy of amikacin products in clinical use in Colombia using this animal model. RESULTS: All except one generic product...

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Detalles Bibliográficos
Autores principales: Zuluaga, Andres F., Rodriguez, Carlos A., Agudelo, Maria, Vesga, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596513/
https://www.ncbi.nlm.nih.gov/pubmed/26445936
http://dx.doi.org/10.1186/s13104-015-1507-z