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Leptin Is Required for Glucose Homeostasis after Roux-en-Y Gastric Bypass in Mice
BACKGROUND & AIMS: Leptin, the protein product of the ob gene, increases energy expenditure and reduces food intake, thereby promoting weight reduction. Leptin also regulates glucose homeostasis and hepatic insulin sensitivity via hypothalamic proopiomelanocortin neurons in mice. Roux-en-Y gastr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596552/ https://www.ncbi.nlm.nih.gov/pubmed/26445459 http://dx.doi.org/10.1371/journal.pone.0139960 |