Leptin Is Required for Glucose Homeostasis after Roux-en-Y Gastric Bypass in Mice

BACKGROUND & AIMS: Leptin, the protein product of the ob gene, increases energy expenditure and reduces food intake, thereby promoting weight reduction. Leptin also regulates glucose homeostasis and hepatic insulin sensitivity via hypothalamic proopiomelanocortin neurons in mice. Roux-en-Y gastr...

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Detalles Bibliográficos
Autores principales: Mokadem, Mohamad, Zechner, Juliet F., Uchida, Aki, Aguirre, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596552/
https://www.ncbi.nlm.nih.gov/pubmed/26445459
http://dx.doi.org/10.1371/journal.pone.0139960

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