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Strain Selection for Generation of O-Antigen-Based Glycoconjugate Vaccines against Invasive Nontyphoidal Salmonella Disease

Nontyphoidal Salmonellae, principally S. Typhimurium and S. Enteritidis, are a major cause of invasive bloodstream infections in sub-Saharan Africa with no vaccine currently available. Conjugation of lipopolysaccharide O-antigen to a carrier protein constitutes a promising vaccination strategy. Here...

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Detalles Bibliográficos
Autores principales: Lanzilao, Luisa, Stefanetti, Giuseppe, Saul, Allan, MacLennan, Calman A., Micoli, Francesca, Rondini, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596569/
https://www.ncbi.nlm.nih.gov/pubmed/26445460
http://dx.doi.org/10.1371/journal.pone.0139847