Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening

The Alanine-Serine-Cysteine transporter ASCT2 (SLC1A5) is a membrane protein that transports neutral amino acids into cells in exchange for outward movement of intracellular amino acids. ASCT2 is highly expressed in peripheral tissues such as the lung and intestines where it contributes to the homeo...

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Detalles Bibliográficos
Autores principales: Colas, Claire, Grewer, Christof, Otte, Nicholas James, Gameiro, Armanda, Albers, Thomas, Singh, Kurnvir, Shere, Helen, Bonomi, Massimiliano, Holst, Jeff, Schlessinger, Avner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596572/
https://www.ncbi.nlm.nih.gov/pubmed/26444490
http://dx.doi.org/10.1371/journal.pcbi.1004477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596572/
https://www.ncbi.nlm.nih.gov/pubmed/26444490
http://dx.doi.org/10.1371/journal.pcbi.1004477

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