Axon injury triggers EFA-6 mediated destabilization of axonal microtubules via TACC and doublecortin like kinase

Axon injury triggers a series of changes in the axonal cytoskeleton that are prerequisites for effective axon regeneration. In Caenorhabditis elegans the signaling protein Exchange Factor for ARF-6 (EFA-6) is a potent intrinsic inhibitor of axon regrowth. Here we show that axon injury triggers rapid...

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Detalles Bibliográficos
Autores principales: Chen, Lizhen, Chuang, Marian, Koorman, Thijs, Boxem, Mike, Jin, Yishi, Chisholm, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596636/
https://www.ncbi.nlm.nih.gov/pubmed/26339988
http://dx.doi.org/10.7554/eLife.08695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596636/
https://www.ncbi.nlm.nih.gov/pubmed/26339988
http://dx.doi.org/10.7554/eLife.08695

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