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Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish

During development, proliferation must be tightly controlled for organs to reach their appropriate size. While the Hippo signaling pathway plays a major role in organ growth control, how it senses and responds to increased cell density is still unclear. In this study, we use the zebrafish lateral li...

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Detalles Bibliográficos
Autores principales: Agarwala, Sobhika, Duquesne, Sandra, Liu, Kun, Boehm, Anton, Grimm, Lin, Link, Sandra, König, Sabine, Eimer, Stefan, Ronneberger, Olaf, Lecaudey, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596637/
https://www.ncbi.nlm.nih.gov/pubmed/26335201
http://dx.doi.org/10.7554/eLife.08201