Cargando…

Transcriptome Analysis of CD4+ T Cells in Coeliac Disease Reveals Imprint of BACH2 and IFNγ Regulation

Genetic studies have to date identified 43 genome wide significant coeliac disease susceptibility (CD) loci comprising over 70 candidate genes. However, how altered regulation of such disease associated genes contributes to CD pathogenesis remains to be elucidated. Recently there has been considerab...

Descripción completa

Detalles Bibliográficos
Autores principales: Quinn, Emma M., Coleman, Ciara, Molloy, Ben, Dominguez Castro, Patricia, Cormican, Paul, Trimble, Valerie, Mahmud, Nasir, McManus, Ross
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596691/
https://www.ncbi.nlm.nih.gov/pubmed/26444573
http://dx.doi.org/10.1371/journal.pone.0140049