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Affinity Inequality among Serum Antibodies That Originate in Lymphoid Germinal Centers
Upon natural infection with pathogens or vaccination, antibodies are produced by a process called affinity maturation. As affinity maturation ensues, average affinity values between an antibody and ligand increase with time. Purified antibodies isolated from serum are invariably heterogeneous with r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596808/ https://www.ncbi.nlm.nih.gov/pubmed/26444899 http://dx.doi.org/10.1371/journal.pone.0139222 |