FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2

Glioblastoma (GBM) is the most aggressive and most lethal brain tumor. As current standard therapy consisting of surgery and chemo-irradiation provides limited benefit for GBM patients, novel therapeutic options are urgently required. Forkhead box M1 (FoxM1) transcription factor is an oncogenic regu...

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Detalles Bibliográficos
Autores principales: Lee, Yeri, Kim, Kang Ho, Kim, Dong Geon, Cho, Hee Jin, Kim, Yeonghwan, Rheey, Jinguen, Shin, Kayoung, Seo, Yun Jee, Choi, Yeon-Sook, Lee, Jung-Il, Lee, Jeongwu, Joo, Kyeung Min, Nam, Do-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596841/
https://www.ncbi.nlm.nih.gov/pubmed/26444992
http://dx.doi.org/10.1371/journal.pone.0137703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596841/
https://www.ncbi.nlm.nih.gov/pubmed/26444992
http://dx.doi.org/10.1371/journal.pone.0137703

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