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Endoplasmic Reticulum Stress-Induced Autophagy Provides Cytoprotection from Chemical Hypoxia and Oxidant Injury and Ameliorates Renal Ischemia-Reperfusion Injury

We examined whether endoplasmic reticulum (ER) stress-induced autophagy provides cytoprotection from renal tubular epithelial cell injury due to oxidants and chemical hypoxia in vitro, as well as from ischemia-reperfusion (IR) injury in vivo. We demonstrate that the ER stress inducer tunicamycin tri...

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Detalles Bibliográficos
Autores principales: Chandrika, Bhavya B., Yang, Cheng, Ou, Yang, Feng, Xiaoke, Muhoza, Djamali, Holmes, Alexandrea F., Theus, Sue, Deshmukh, Sarika, Haun, Randy S., Kaushal, Gur P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596863/
https://www.ncbi.nlm.nih.gov/pubmed/26444017
http://dx.doi.org/10.1371/journal.pone.0140025