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The Role of Efflux Pumps in Schistosoma mansoni Praziquantel Resistant Phenotype

BACKGROUND: Schistosomiasis is a neglected disease caused by a trematode of the genus Schistosoma that is second only to malaria in public health significance in Africa, South America, and Asia. Praziquantel (PZQ) is the drug of choice to treat this disease due to its high cure rates and no signific...

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Detalles Bibliográficos
Autores principales: Pinto-Almeida, António, Mendes, Tiago, Armada, Ana, Belo, Silvana, Carrilho, Emanuel, Viveiros, Miguel, Afonso, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596880/
https://www.ncbi.nlm.nih.gov/pubmed/26445012
http://dx.doi.org/10.1371/journal.pone.0140147