Cargando…

The Role of Efflux Pumps in Schistosoma mansoni Praziquantel Resistant Phenotype

BACKGROUND: Schistosomiasis is a neglected disease caused by a trematode of the genus Schistosoma that is second only to malaria in public health significance in Africa, South America, and Asia. Praziquantel (PZQ) is the drug of choice to treat this disease due to its high cure rates and no signific...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pinto-Almeida, António, Mendes, Tiago, Armada, Ana, Belo, Silvana, Carrilho, Emanuel, Viveiros, Miguel, Afonso, Ana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596880/ https://www.ncbi.nlm.nih.gov/pubmed/26445012 http://dx.doi.org/10.1371/journal.pone.0140147

Ejemplares similares

Morphological Characteristics of Schistosoma mansoni PZQ-Resistant and -Susceptible Strains Are Different in Presence of Praziquantel
por: Pinto-Almeida, António, et al.
Publicado: (2016)

THE SUSCEPTIBILITY OF RECENT ISOLATES OF Schistosoma mansoni TO PRAZIQUANTEL
por: MENDONÇA, Adriana Maria B., et al.
Publicado: (2016)

Praziquantel-encapsulated niosomes against Schistosoma mansoni with reduced sensitivity to praziquantel
por: Amer, Eglal I., et al.
Publicado: (2022)

Investigations on the interplays between Schistosoma mansoni, praziquantel and the gut microbiome
por: Schneeberger, Pierre H. H., et al.
Publicado: (2018)

A single locus determines praziquantel response in Schistosoma mansoni
por: Chevalier, Frédéric D., et al.
Publicado: (2023)

Synergy of Omeprazole and Praziquantel In Vitro Treatment against Schistosoma mansoni Adult Worms
por: Almeida, Giulliana T., et al.
Publicado: (2015)

Praziquantel Treatment Decreases Schistosoma mansoni Genetic Diversity in Experimental Infections
por: Coeli, Regina, et al.
Publicado: (2013)

Evaluation of the pharmacokinetic-pharmacodynamic relationship of praziquantel in the Schistosoma mansoni mouse model
por: Abla, Nada, et al.
Publicado: (2017)

Effect of Dihydroartemisinin-Piperaquine on the Pharmacokinetics of Praziquantel for Treatment of Schistosoma mansoni Infection
por: Minzi, Omary Mashiku, et al.
Publicado: (2021)

Reduced Susceptibility to Praziquantel among Naturally Occurring Kenyan Isolates of Schistosoma mansoni
por: Melman, Sandra D., et al.
Publicado: (2009)

Praziquantel–lipid nanocapsules: an oral nanotherapeutic with potential Schistosoma mansoni tegumental targeting
por: Amara, Rokaya O, et al.
Publicado: (2018)

Efficacy and Safety of Praziquantel for Treatment of Schistosoma mansoni Infection among School Children in Tanzania
por: Mnkugwe, Rajabu Hussein, et al.
Publicado: (2019)

Schistosoma mansoni alter transcription of immunomodulatory gene products following in vivo praziquantel exposure
por: McCusker, Paul, et al.
Publicado: (2021)

Praziquantel Treatment of Schistosoma mansoni Infected Mice Renders Them Less Susceptible to Reinfection
por: Nono, Justin Komguep, et al.
Publicado: (2021)

Protein undernutrition reduces the efficacy of praziquantel in a murine model of Schistosoma mansoni infection
por: Kadji Fassi, Joseph Bertin, et al.
Publicado: (2022)

Effect of Maternal Schistosoma mansoni Infection and Praziquantel Treatment During Pregnancy on Schistosoma mansoni Infection and Immune Responsiveness among Offspring at Age Five Years
por: Tweyongyere, Robert, et al.
Publicado: (2013)

In Vitro Praziquantel Test Capable of Detecting Reduced In Vivo Efficacy in Schistosoma mansoni Human Infections
por: Lamberton, Poppy H. L., et al.
Publicado: (2010)

Efficacy and Safety of Praziquantel in Preschool-Aged Children in an Area Co-Endemic for Schistosoma mansoni and S. haematobium
por: Coulibaly, Jean T., et al.
Publicado: (2012)

Reduced Efficacy of Praziquantel Against Schistosoma mansoni Is Associated With Multiple Rounds of Mass Drug Administration
por: Crellen, Thomas, et al.
Publicado: (2016)

In vivo assessment of the antischistosomal activity of curcumin loaded nanoparticles versus praziquantel in the treatment of Schistosoma mansoni
por: Mokbel, Kamal El-Din M., et al.
Publicado: (2020)

The antioxidants resveratrol and N-acetylcysteine enhance anthelmintic activity of praziquantel and artesunate against Schistosoma mansoni
por: Gouveia, Maria João, et al.
Publicado: (2019)

Efficacy of Single-Dose Praziquantel for the Treatment of Schistosoma mansoni Infections among School Children in Rwanda
por: Kabatende, Joseph, et al.
Publicado: (2023)

Curcumin Generates Oxidative Stress and Induces Apoptosis in Adult Schistosoma mansoni Worms
por: de Paula Aguiar, Daniela, et al.
Publicado: (2016)

Comparison of the in vitro Effects of One-day Exposure to Amodiaquine and Praziquantel on Schistosoma mansoni Adult Worm Pairs
por: Mitsui, Yoshinori
Publicado: (2014)

Praziquantel sensitivity of Kenyan Schistosoma mansoni isolates and the generation of a laboratory strain with reduced susceptibility to the drug
por: Mwangi, Ibrahim N., et al.
Publicado: (2014)

Evaluation of the Anti-schistosomal Effects of Turmeric (Curcuma longa) Versus Praziquantel in Schistosoma mansoni Infected Mice
por: HUSSEIN, Atef, et al.
Publicado: (2017)

The effects of subcurative praziquantel treatment on life‐history traits and trade‐offs in drug‐resistant Schistosoma mansoni
por: Viana, Mafalda, et al.
Publicado: (2017)

Complementary Effect of Capparis Spinosa L. and Silymarin With/without Praziquantel on Mice Experimentally Infected with Schistosoma Mansoni
por: El-Hawary, S. S., et al.
Publicado: (2018)

Praziquantel is an effective drug for the treatment of Schistosoma Mansoni infection among school-aged children in Northwest Ethiopia
por: Tesfie, Addisu, et al.
Publicado: (2020)

Pathological and immunological evaluation of different regimens of praziquantel treatment in a mouse model of Schistosoma mansoni infection
por: Membe Femoe, Ulrich, et al.
Publicado: (2022)

Immunization with tegument nucleotidases associated with a subcurative praziquantel treatment reduces worm burden following Schistosoma mansoni challenge
por: Rofatto, Henrique K., et al.
Publicado: (2013)

Multidrug Efflux Pumps in Staphylococcus aureus: an Update
por: Costa, Sofia Santos, et al.
Publicado: (2013)

Efficacy and Safety of Moxidectin, Synriam, Synriam-Praziquantel versus Praziquantel against Schistosoma haematobium and S. mansoni Infections: A Randomized, Exploratory Phase 2 Trial
por: Barda, Beatrice, et al.
Publicado: (2016)

Efficacy of Mebendazole and Praziquantel against Soil-Transmitted Helminths and Schistosoma mansoni Infections among Schoolchildren in Northwest Ethiopia
por: Ejigu, Kefale, et al.
Publicado: (2021)

Efficacy of Praziquantel Treatment and Schistosoma Mansoni Infection among Primary School Children in Kemisse Town, Northeast Ethiopia
por: Berhanu, Meslo Sema, et al.
Publicado: (2022)

ABC Efflux Transporters and the Circuitry of miRNAs: Kinetics of Expression in Cancer Drug Resistance
por: Gomes, Bruno C., et al.
Publicado: (2020)

Observed Reductions in Schistosoma mansoni Transmission from Large-Scale Administration of Praziquantel in Uganda: A Mathematical Modelling Study
por: French, Michael D., et al.
Publicado: (2010)

Anti-inflammatory/anti-fibrotic effects of the hepatoprotective silymarin and the schistosomicide praziquantel against Schistosoma mansoni-induced liver fibrosis
por: El-Lakkany, Naglaa M, et al.
Publicado: (2012)

Evaluation of Schistosoma Mansoni Morbidity One Year After Praziquantel Treatment in Rhino Camp and Obongi in West Nile, Uganda
por: Odongo-Aginya, E I, et al.
Publicado: (2010)

Antiparasitic Activity of Mirazid, Myrrh Total Oil and Nitazoxanide Compared to Praziquantel on Schistosoma mansoni: Scanning Electron Microscopic Study
por: EL-SAYAD, Mona, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_so68d7rplgbrjajv7n63s9osm1