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Decreased RXRα is Associated with Increased β-Catenin/TCF4 in (56)Fe-Induced Intestinal Tumors

Although it is known that accumulation of oncogenic β-catenin is critical for intestinal tumorigenesis, the underlying mechanisms have not yet been fully explored. Post-translational β-catenin level is regulated via the adenomatous polyposis coli (APC)-dependent as well as the APC-independent ubiqui...

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Detalles Bibliográficos
Autores principales: Suman, Shubhankar, Kumar, Santosh, Fornace, Albert J., Datta, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597120/
https://www.ncbi.nlm.nih.gov/pubmed/26500891
http://dx.doi.org/10.3389/fonc.2015.00218