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Microbiota-Specific CD4CD8αα Tregs: Role in Intestinal Immune Homeostasis and Implications for IBD

In studies in murine models, active suppression by IL-10-secreting Foxp3 regulatory T cells (Tregs) has emerged as an essential mechanism in colon homeostasis. However, the role of the equivalent subset in humans remains unclear, leading to suggestions that other subsets and/or mechanisms may substi...

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Detalles Bibliográficos
Autores principales: Sarrabayrouse, Guillaume, Alameddine, Joudy, Altare, Frédéric, Jotereau, Francine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597122/
https://www.ncbi.nlm.nih.gov/pubmed/26500657
http://dx.doi.org/10.3389/fimmu.2015.00522