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Understanding and predicting binding between human leukocyte antigens (HLAs) and peptides by network analysis
BACKGROUND: As the major histocompatibility complex (MHC), human leukocyte antigens (HLAs) are one of the most polymorphic genes in humans. Patients carrying certain HLA alleles may develop adverse drug reactions (ADRs) after taking specific drugs. Peptides play an important role in HLA related ADRs...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597169/ https://www.ncbi.nlm.nih.gov/pubmed/26424483 http://dx.doi.org/10.1186/1471-2105-16-S13-S9 |