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Understanding and predicting binding between human leukocyte antigens (HLAs) and peptides by network analysis

BACKGROUND: As the major histocompatibility complex (MHC), human leukocyte antigens (HLAs) are one of the most polymorphic genes in humans. Patients carrying certain HLA alleles may develop adverse drug reactions (ADRs) after taking specific drugs. Peptides play an important role in HLA related ADRs...

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Detalles Bibliográficos
Autores principales:	Luo, Heng, Ye, Hao, Ng, Hui Wen, Shi, Leming, Tong, Weida, Mattes, William, Mendrick, Donna, Hong, Huixiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597169/ https://www.ncbi.nlm.nih.gov/pubmed/26424483 http://dx.doi.org/10.1186/1471-2105-16-S13-S9

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