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FSP1(+) fibroblast subpopulation is essential for the maintenance and regeneration of medullary thymic epithelial cells
Thymic epithelial cells (TECs) form a 3-dimentional network supporting thymocyte development and maturation. Besides epithelium and thymocytes, heterogeneous fibroblasts are essential components in maintaining thymic microenvironments. However, thymic fibroblast characteristics, development and func...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597222/ https://www.ncbi.nlm.nih.gov/pubmed/26445893 http://dx.doi.org/10.1038/srep14871 |