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The antiviral drug ganciclovir does not inhibit microglial proliferation and activation

Ganciclovir is effective in the treatment of human infections with viruses of the Herpesviridae family. Beside antiviral properties, recently ganciclovir was described to inhibit microglial proliferation and disease severity of experimental autoimmune encephalomyelitis, an inflammatory model of mult...

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Detalles Bibliográficos
Autores principales: Skripuletz, Thomas, Salinas Tejedor, Laura, Prajeeth, Chittappen K., Hansmann, Florian, Chhatbar, Chintan, Kucman, Valeria, Zhang, Ning, Raddatz, Barbara B., Detje, Claudia N., Sühs, Kurt-Wolfram, Pul, Refik, Gudi, Viktoria, Kalinke, Ulrich, Baumgärtner, Wolfgang, Stangel, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597339/
https://www.ncbi.nlm.nih.gov/pubmed/26447351
http://dx.doi.org/10.1038/srep14935