Cargando…

All-trans retinoic acid arrests cell cycle in leukemic bone marrow stromal cells by increasing intercellular communication through connexin 43-mediated gap junction

BACKGROUND: Gap junctional intercellular communication (GJIC) is typically decreased in malignant tumors. Gap junction is not presented between hematopoietic cells but occurred in bone marrow stromal cells (BMSCs). Connexin 43 (Cx43) is the major gap junction (GJ) protein; our previous study reveale...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yao, Wen, Qin, Chen, Xue-lian, Yang, Shi-jie, Gao, Lei, Gao, Li, Zhang, Cheng, Li, Jia-li, Xiang, Xi-xi, Wan, Kai, Chen, Xing-hua, Zhang, Xi, Zhong, Jiang-fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597383/
https://www.ncbi.nlm.nih.gov/pubmed/26446715
http://dx.doi.org/10.1186/s13045-015-0212-7