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RNA sequencing reveals a depletion of collagen targeting microRNAs in Dupuytren’s disease
BACKGROUND: Dupuytren’s disease is an inherited disorder in which patients develop fibrotic contractures of the hand. Current treatment strategies include surgical excision or enzymatic digestion of fibrotic tissue. MicroRNAs, which are key posttranscriptional regulators of genes expression, have be...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597401/ https://www.ncbi.nlm.nih.gov/pubmed/26446724 http://dx.doi.org/10.1186/s12920-015-0135-8 |