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RNA sequencing reveals a depletion of collagen targeting microRNAs in Dupuytren’s disease

BACKGROUND: Dupuytren’s disease is an inherited disorder in which patients develop fibrotic contractures of the hand. Current treatment strategies include surgical excision or enzymatic digestion of fibrotic tissue. MicroRNAs, which are key posttranscriptional regulators of genes expression, have be...

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Detalles Bibliográficos
Autores principales: Riester, Scott M., Arsoy, Diren, Camilleri, Emily T., Dudakovic, Amel, Paradise, Christopher R., Evans, Jared M., Torres-Mora, Jorge, Rizzo, Marco, Kloen, Peter, Julio, Marianna Kruithof-de, van Wijnen, Andre J., Kakar, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597401/
https://www.ncbi.nlm.nih.gov/pubmed/26446724
http://dx.doi.org/10.1186/s12920-015-0135-8