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Circulating nucleosomes as epigenetic biomarkers in pancreatic cancer

BACKGROUND: To improve the prognosis of patients with pancreatic cancer, new biomarkers are required for earlier, pre-symptomatic diagnosis. Epigenetic mutations take place at the earliest stages of tumorigenesis and therefore offer new approaches for detecting and diagnosing disease. Nucleosomes ar...

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Detalles Bibliográficos
Autores principales: Bauden, Monika, Pamart, Dorian, Ansari, Daniel, Herzog, Marielle, Eccleston, Mark, Micallef, Jake, Andersson, Bodil, Andersson, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597435/
https://www.ncbi.nlm.nih.gov/pubmed/26451166
http://dx.doi.org/10.1186/s13148-015-0139-4