Corin is down-regulated and exerts cardioprotective action via activating pro-atrial natriuretic peptide pathway in diabetic cardiomyopathy

BACKGROUND: Diabetic cardiomyopathy (DCM), a fatal cardiovascular complication of diabetes mellitus, often leads to progressive heart failure, however its pathogenesis remains unclear. Corin, a cardiac serine protease, is responsible for converting pro-atrial natriuretic peptide (pro-ANP) to biologi...

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Detalles Bibliográficos
Autores principales: Pang, Aiming, Hu, Yahui, Zhou, Pengfei, Long, Guangfeng, Tian, Xin, Men, Li, Shen, Yanna, Liu, Yunde, Cui, Yujie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597453/
https://www.ncbi.nlm.nih.gov/pubmed/26446774
http://dx.doi.org/10.1186/s12933-015-0298-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597453/
https://www.ncbi.nlm.nih.gov/pubmed/26446774
http://dx.doi.org/10.1186/s12933-015-0298-9

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