Exclusive Association of p53 Mutation with Super-High Methylation of Tumor Suppressor Genes in the p53 Pathway in a Unique Gastric Cancer Phenotype

BACKGROUND: A comprehensive search for DNA methylated genes identified candidate tumor suppressor genes that have been proven to be involved in the apoptotic process of the p53 pathway. In this study, we investigated p53 mutation in relation to such epigenetic alteration in primary gastric cancer. M...

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Detalles Bibliográficos
Autores principales: Waraya, Mina, Yamashita, Keishi, Ema, Akira, Katada, Natsuya, Kikuchi, Shiro, Watanabe, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598091/
https://www.ncbi.nlm.nih.gov/pubmed/26447864
http://dx.doi.org/10.1371/journal.pone.0139902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598091/
https://www.ncbi.nlm.nih.gov/pubmed/26447864
http://dx.doi.org/10.1371/journal.pone.0139902

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