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Physiologically Shrinking the Solution Space of a Saccharomyces cerevisiae Genome-Scale Model Suggests the Role of the Metabolic Network in Shaping Gene Expression Noise

Sampling the solution space of genome-scale models is generally conducted to determine the feasible region for metabolic flux distribution. Because the region for actual metabolic states resides only in a small fraction of the entire space, it is necessary to shrink the solution space to improve the...

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Detalles Bibliográficos
Autores principales: Chi, Baofang, Tao, Shiheng, Liu, Yanlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598104/
https://www.ncbi.nlm.nih.gov/pubmed/26448560
http://dx.doi.org/10.1371/journal.pone.0139590