Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression

BACKGROUND: The use of temozolomide (TMZ) has improved the prognosis for glioblastoma multiforme patients. However, TMZ resistance may be one of the main reasons why treatment fails. Although this resistance has frequently been linked to the expression of O6-methylguanine-DNA methyltransferase (MGMT...

Descripción completa

Detalles Bibliográficos
Autores principales: Perazzoli, Gloria, Prados, Jose, Ortiz, Raul, Caba, Octavio, Cabeza, Laura, Berdasco, Maria, Gónzalez, Beatriz, Melguizo, Consolación
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598115/
https://www.ncbi.nlm.nih.gov/pubmed/26447477
http://dx.doi.org/10.1371/journal.pone.0140131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598115/
https://www.ncbi.nlm.nih.gov/pubmed/26447477
http://dx.doi.org/10.1371/journal.pone.0140131

Ejemplares similares