Generation of New Hairless Alleles by Genomic Engineering at the Hairless Locus in Drosophila melanogaster

Hairless (H) is the major antagonist within the Notch signalling pathway of Drosophila melanogaster. By binding to Suppressor of Hairless [Su(H)] and two co-repressors, H induces silencing of Notch target genes in the absence of Notch signals. We have applied genomic engineering to create several ne...

Descripción completa

Detalles Bibliográficos
Autores principales: Praxenthaler, Heiko, Smylla, Thomas K., Nagel, Anja C., Preiss, Anette, Maier, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598140/
https://www.ncbi.nlm.nih.gov/pubmed/26448463
http://dx.doi.org/10.1371/journal.pone.0140007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598140/
https://www.ncbi.nlm.nih.gov/pubmed/26448463
http://dx.doi.org/10.1371/journal.pone.0140007

Ejemplares similares