Age-Dependent Defects of Regulatory B Cells in Wiskott-Aldrich Syndrome Gene Knockout Mice

The Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency characterized by recurrent infections, thrombocytopenia, eczema, and high incidence of malignancy and autoimmunity. The cellular mechanisms underlying autoimmune complications in WAS have been extensively studied; however...

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Detalles Bibliográficos
Autores principales: Yokoyama, Tadafumi, Yoshizaki, Ayumi, Simon, Karen L., Kirby, Martha R., Anderson, Stacie M., Candotti, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598155/
https://www.ncbi.nlm.nih.gov/pubmed/26448644
http://dx.doi.org/10.1371/journal.pone.0139729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598155/
https://www.ncbi.nlm.nih.gov/pubmed/26448644
http://dx.doi.org/10.1371/journal.pone.0139729

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