The Cannabinoid Receptor 2 Q63R Variant Modulates the Relationship between Childhood Obesity and Age at Menarche

BACKGROUND: The ovary is an important site where gene variants modulate pubertal timing. The cannabinoid receptor 2 (CB2) is expressed in the ovary, plays a role in folliculogenesis and ovulation, and can be modulated by estrogens. Obesity is strictly associated with early menarche and is characteri...

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Detalles Bibliográficos
Autores principales: Bellini, Giulia, Grandone, Anna, Torella, Marco, Miraglia del Giudice, Emanuele, Nobili, Bruno, Perrone, Laura, Maione, Sabatino, Rossi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598176/
https://www.ncbi.nlm.nih.gov/pubmed/26447698
http://dx.doi.org/10.1371/journal.pone.0140142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598176/
https://www.ncbi.nlm.nih.gov/pubmed/26447698
http://dx.doi.org/10.1371/journal.pone.0140142

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