Cargando…

The Cannabinoid Receptor 2 Q63R Variant Modulates the Relationship between Childhood Obesity and Age at Menarche

BACKGROUND: The ovary is an important site where gene variants modulate pubertal timing. The cannabinoid receptor 2 (CB2) is expressed in the ovary, plays a role in folliculogenesis and ovulation, and can be modulated by estrogens. Obesity is strictly associated with early menarche and is characteri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bellini, Giulia, Grandone, Anna, Torella, Marco, Miraglia del Giudice, Emanuele, Nobili, Bruno, Perrone, Laura, Maione, Sabatino, Rossi, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598176/ https://www.ncbi.nlm.nih.gov/pubmed/26447698 http://dx.doi.org/10.1371/journal.pone.0140142

Ejemplares similares

Cannabinoid Receptor Type 2 Functional Variant Influences Liver Damage in Children with Non-Alcoholic Fatty Liver Disease
por: Rossi, Francesca, et al.
Publicado: (2012)

Cannabinoid Receptor 2-63 QQ Variant Is Associated with Persistently Normal Aminotransferase Serum Levels in Chronic Hepatitis C
por: Coppola, Nicola, et al.
Publicado: (2014)

The role of cannabinoid receptor 2 in oligo/poly-articular juvenile idiopathic arthritis
por: Gicchino, Maria F, et al.
Publicado: (2014)

Chromosome 16p11.2 deletions: another piece in the genetic puzzle of childhood obesity
por: Perrone, Laura, et al.
Publicado: (2010)

Thyroid function derangement and childhood obesity: an Italian experience
por: Grandone, Anna, et al.
Publicado: (2010)

The Association of PNPLA3 Variants with Liver Enzymes in Childhood Obesity Is Driven by the Interaction with Abdominal Fat
por: Miraglia del Giudice, Emanuele, et al.
Publicado: (2011)

Iron Metabolism Dysregulation and Cognitive Dysfunction in Pediatric Obesity: Is There a Connection?
por: Grandone, Anna, et al.
Publicado: (2015)

Role of Cannabinoids in Obesity
por: Rossi, Francesca, et al.
Publicado: (2018)

The Cannabinoid Receptor Type 2 as Mediator of Mesenchymal Stromal Cell Immunosuppressive Properties
por: Rossi, Francesca, et al.
Publicado: (2013)

Subclinical Myocardial Dysfunction and Cardiac Autonomic Dysregulation Are Closely Associated in Obese Children and Adolescents: The Potential Role of Insulin Resistance
por: Cozzolino, Domenico, et al.
Publicado: (2015)

A case of familial central precocious puberty caused by a novel mutation in the makorin RING finger protein 3 gene
por: Grandone, Anna, et al.
Publicado: (2015)

The Role of Cannabinoid Receptors in the Descending Modulation of Pain
por: Palazzo, Enza, et al.
Publicado: (2010)

Cannabinoid receptor 2-63 RR variant is independently associated with severe necroinflammation in HIV/HCV coinfected patients
por: Sagnelli, Caterina, et al.
Publicado: (2017)

Very early onset of autoimmune thyroiditis in a toddler with severe hypothyroidism presentation: a case report
por: Marzuillo, Pierluigi, et al.
Publicado: (2016)

Genetic Evaluation of Patients With Delayed Puberty and Congenital Hypogonadotropic Hypogonadism: Is it Worthy of Consideration?
por: Festa, Adalgisa, et al.
Publicado: (2020)

Novel cAMP binding protein-BP (CREBBP) mutation in a girl with Rubinstein-Taybi syndrome, GH deficiency, Arnold Chiari malformation and pituitary hypoplasia
por: Marzuillo, Pierluigi, et al.
Publicado: (2013)

Predicting Metabolic Syndrome in Obese Children and Adolescents: Look, Measure and Ask
por: Santoro, Nicola, et al.
Publicado: (2013)

Clinical and surgical management of unilateral prepubertal gynecomastia
por: Ferraro, Giuseppe Andrea, et al.
Publicado: (2014)

MKRN3 role in regulating pubertal onset: the state of art of functional studies
por: Palumbo, Stefania, et al.
Publicado: (2022)

Circulating levels of DLK1 and glucose homeostasis in girls with obesity: A pilot study
por: Palumbo, Stefania, et al.
Publicado: (2022)

Mendelian Randomisation Study of Childhood BMI and Early Menarche
por: Mumby, Hannah S., et al.
Publicado: (2011)

Early menarche and childhood adversities in a nationally representative sample
por: Henrichs, Kimberly L, et al.
Publicado: (2014)

Maternal age at menarche and offspring body mass index in childhood
por: Wang, Hui, et al.
Publicado: (2019)

Molecular screening of PROKR2 gene in girls with idiopathic central precocious puberty
por: Aiello, Francesca, et al.
Publicado: (2021)

Omics era in type 2 diabetes: From childhood to adulthood
por: Passaro, Antonio Paride, et al.
Publicado: (2021)

Determinants of menarche
por: Karapanou, Olga, et al.
Publicado: (2010)

The relation of menarcheal age to obesity in childhood and adulthood: the Bogalusa heart study
por: Freedman, David S, et al.
Publicado: (2003)

Childhood and adolescent phenol and phthalate exposure and the age of menarche in Latina girls
por: Binder, Alexandra M., et al.
Publicado: (2018)

Case report: Goiter and overt hypothyroidism in an iodine-deficient toddler on soy milk and hypoallergenic diet
por: Caprio, Angela Maria, et al.
Publicado: (2022)

Earlier Mother's Age at Menarche Predicts Rapid Infancy Growth and Childhood Obesity
por: Ong, Ken K, et al.
Publicado: (2007)

Influence of Childhood Adversity and Infection on Timing of Menarche in a Multiethnic Sample of Women
por: April-Sanders, Ayana K., et al.
Publicado: (2021)

Longitudinal association of dietary sources of animal and plant protein throughout childhood with menarche
por: Moslehi, Nazanin, et al.
Publicado: (2021)

Relationship between nonalcoholic fatty liver disease and chronic kidney disease could start in childhood
por: Di Sessa, Anna, et al.
Publicado: (2021)

Central precocious puberty during COVID-19 pandemic and sleep disturbance: an exploratory study
por: Umano, Giuseppina R, et al.
Publicado: (2022)

Bifidobacterium mixture (B longum BB536, B infantis M-63, B breve M-16V) treatment in children with seasonal allergic rhinitis and intermittent asthma
por: Del Giudice, Michele Miraglia, et al.
Publicado: (2017)

Functional variation (Q63R) in the cannabinoid CB2 receptor may affect the severity of COVID-19: a human study and molecular docking
por: Rastegar, Mostafa, et al.
Publicado: (2021)

Systematic review and meta‐analysis of the association between childhood physical activity and age at menarche
por: Calthorpe, Lucia, et al.
Publicado: (2019)

Association between Hepatic Steatosis and Obstructive Sleep Apnea in Children and Adolescents with Obesity
por: Carotenuto, Marco, et al.
Publicado: (2021)

Effect of COVID-19 Lockdown on Children’s Eating Behaviours: A Longitudinal Study
por: Umano, Giuseppina Rosaria, et al.
Publicado: (2022)

Age at menarche does not correlate with the endometriosis phenotype
por: Marcellin, Louis, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_i2mr08u2us2i1il256e6v42o50