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Nanoparticulated docetaxel exerts enhanced anticancer efficacy and overcomes existing limitations of traditional drugs

Nanoparticulation of insoluble drugs improves dissolution rate, resulting in increased bioavailability that leads to increased stability, better efficacy, and reduced toxicity of drugs. Docetaxel (DTX), under the trade name Taxotere™, is one of the representative anticancer chemotherapeutic agents o...

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Detalles Bibliográficos
Autores principales: Choi, Jinhyang, Ko, Eunjung, Chung, Hye-Kyung, Lee, Jae Hee, Ju, Eun Jin, Lim, Hyun Kyung, Park, Intae, Kim, Kab-Sig, Lee, Joo-Hwan, Son, Woo-Chan, Lee, Jung Shin, Jung, Joohee, Jeong, Seong-Yun, Song, Si Yeol, Choi, Eun Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598197/
https://www.ncbi.nlm.nih.gov/pubmed/26457052
http://dx.doi.org/10.2147/IJN.S88375