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The prostaglandin D(2) receptor CRTH2 regulates accumulation of group 2 innate lymphoid cells in the inflamed lung

Group 2 innate lymphoid cells (ILC2s) promote type 2 cytokine-dependent immunity, inflammation and tissue repair. While epithelial cell-derived cytokines regulate ILC2 effector functions, the pathways that control the in vivo migration of ILC2s into inflamed tissues remain poorly understood. Here, w...

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Detalles Bibliográficos
Autores principales: Tait Wojno, ED, Monticelli, LA, Tran, SV, Alenghat, T, Osborne, LC, Thome, JJ, Willis, C, Budelsky, A, Farber, DL, Artis, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598246/
https://www.ncbi.nlm.nih.gov/pubmed/25850654
http://dx.doi.org/10.1038/mi.2015.21