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ACF chromatin remodeling complex mediates stress–induced depressive–like behavior

Improved treatment for major depressive disorder (MDD) remains elusive due to limited understanding of its underlying biological mechanisms. Stress–induced maladaptive transcriptional regulation within limbic neural circuits likely contributes to the development of MDD, possibly through epigenetic f...

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Detalles Bibliográficos
Autores principales: Sun, HaoSheng, Damez–Werno, Diane M., Scobie, Kimberly N., Shao, Ning–Yi, Dias, Caroline, Rabkin, Jacqui, Koo, Ja Wook, Korb, Erica, Bagot, Rosemary C., Ahn, Francisca H., Cahill, Michael E., Labonté, Benoit, Mouzon, Ezekiell, Heller, Elizabeth A., Cates, Hannah, Golden, Sam A, Gleason, Kelly, Russo, Scott J, Andrews, Simon, Neve, Rachael, Kennedy, Pamela J., Maze, Ian, Dietz, David M., Allis, C. David, Turecki, Gustavo, Varga–Weisz, Patrick, Tamminga, Carol, Shen, Li, Nestler, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598281/
https://www.ncbi.nlm.nih.gov/pubmed/26390241
http://dx.doi.org/10.1038/nm.3939