Maternal bile acid transporter deficiency promotes neonatal demise

Intrahepatic cholestasis of pregnancy (ICP) is associated with adverse neonatal survival and is estimated to impact between 0.4 and 5% of pregnancies worldwide. Here we show that maternal cholestasis (due to Abcb11 deficiency) produces neonatal death among all offspring within 24 h of birth due to a...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanyuan, Li, Fei, Wang, Yao, Pitre, Aaron, Fang, Zhong-ze, Frank, Matthew W., Calabrese, Christopher, Krausz, Kristopher W., Neale, Geoffrey, Frase, Sharon, Vogel, Peter, Rock, Charles O., Gonzalez, Frank J., Schuetz, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598356/
https://www.ncbi.nlm.nih.gov/pubmed/26416771
http://dx.doi.org/10.1038/ncomms9186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598356/
https://www.ncbi.nlm.nih.gov/pubmed/26416771
http://dx.doi.org/10.1038/ncomms9186

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