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Maternal bile acid transporter deficiency promotes neonatal demise
Intrahepatic cholestasis of pregnancy (ICP) is associated with adverse neonatal survival and is estimated to impact between 0.4 and 5% of pregnancies worldwide. Here we show that maternal cholestasis (due to Abcb11 deficiency) produces neonatal death among all offspring within 24 h of birth due to a...
Autores principales: | Zhang, Yuanyuan, Li, Fei, Wang, Yao, Pitre, Aaron, Fang, Zhong-ze, Frank, Matthew W., Calabrese, Christopher, Krausz, Kristopher W., Neale, Geoffrey, Frase, Sharon, Vogel, Peter, Rock, Charles O., Gonzalez, Frank J., Schuetz, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598356/ https://www.ncbi.nlm.nih.gov/pubmed/26416771 http://dx.doi.org/10.1038/ncomms9186 |
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