Structure of the native Sec61 protein-conducting channel

In mammalian cells, secretory and membrane proteins are translocated across or inserted into the endoplasmic reticulum (ER) membrane by the universally conserved protein-conducting channel Sec61, which has been structurally studied in isolated, detergent-solubilized states. Here we structurally and...

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Detalles Bibliográficos
Autores principales: Pfeffer, Stefan, Burbaum, Laura, Unverdorben, Pia, Pech, Markus, Chen, Yuxiang, Zimmermann, Richard, Beckmann, Roland, Förster, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598622/
https://www.ncbi.nlm.nih.gov/pubmed/26411746
http://dx.doi.org/10.1038/ncomms9403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598622/
https://www.ncbi.nlm.nih.gov/pubmed/26411746
http://dx.doi.org/10.1038/ncomms9403

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