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Structure of the native Sec61 protein-conducting channel

In mammalian cells, secretory and membrane proteins are translocated across or inserted into the endoplasmic reticulum (ER) membrane by the universally conserved protein-conducting channel Sec61, which has been structurally studied in isolated, detergent-solubilized states. Here we structurally and...

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Detalles Bibliográficos
Autores principales:	Pfeffer, Stefan, Burbaum, Laura, Unverdorben, Pia, Pech, Markus, Chen, Yuxiang, Zimmermann, Richard, Beckmann, Roland, Förster, Friedrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598622/ https://www.ncbi.nlm.nih.gov/pubmed/26411746 http://dx.doi.org/10.1038/ncomms9403

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