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SDS-PAGE analysis of Aβ oligomers is disserving research into Alzheimer´s disease: appealing for ESI-IM-MS

The characterization of amyloid-beta peptide (Aβ) oligomer forms and structures is crucial to the advancement in the field of Alzheimer´s disease (AD). Here we report a critical evaluation of two methods used for this purpose, namely sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAG...

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Detalles Bibliográficos
Autores principales: Pujol-Pina, Rosa, Vilaprinyó-Pascual, Sílvia, Mazzucato, Roberta, Arcella, Annalisa, Vilaseca, Marta, Orozco, Modesto, Carulla, Natàlia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598734/
https://www.ncbi.nlm.nih.gov/pubmed/26450154
http://dx.doi.org/10.1038/srep14809