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Directed Differentiation of Embryonic Stem Cells Into Cardiomyocytes by Bacterial Injection of Defined Transcription Factors

Forced expression of defined transcriptional factors has been well documented as an effective method for cellular reprogramming or directed differentiation. However, transgene expression is not amenable for therapeutic application due to potential insertional mutagenesis. Here, we have developed a b...

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Detalles Bibliográficos
Autores principales: Bai, Fang, Ho Lim, Chae, Jia, Jingyue, Santostefano, Katherine, Simmons, Chelsey, Kasahara, Hideko, Wu, Weihui, Terada, Naohiro, Jin, Shouguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598736/
https://www.ncbi.nlm.nih.gov/pubmed/26449528
http://dx.doi.org/10.1038/srep15014