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CPI motif interaction is necessary for capping protein function in cells

Capping protein (CP) has critical roles in actin assembly in vivo and in vitro. CP binds with high affinity to the barbed end of actin filaments, blocking the addition and loss of actin subunits. Heretofore, models for actin assembly in cells generally assumed that CP is constitutively active, diffu...

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Detalles Bibliográficos
Autores principales: Edwards, Marc, McConnell, Patrick, Schafer, Dorothy A., Cooper, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598739/
https://www.ncbi.nlm.nih.gov/pubmed/26412145
http://dx.doi.org/10.1038/ncomms9415