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Transcription of Interleukin-8: How Altered Regulation Can Affect Cystic Fibrosis Lung Disease
Interleukin-8 (IL-8) is a neutrophil chemokine that is encoded on the CXCL8 gene. Normally CXCL8 expression is repressed due to histone deacetylation, octamer-1 binding to the promoter and the inhibitory effect of nuclear factor-κB repressing factor (NRF). However, in response to a suitable stimulus...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598756/ https://www.ncbi.nlm.nih.gov/pubmed/26140537 http://dx.doi.org/10.3390/biom5031386 |