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Comprehensive Protein Interactome Analysis of a Key RNA Helicase: Detection of Novel Stress Granule Proteins

DDX6 (p54/RCK) is a human RNA helicase with central roles in mRNA decay and translation repression. To help our understanding of how DDX6 performs these multiple functions, we conducted the first unbiased, large-scale study to map the DDX6-centric protein-protein interactome using immunoprecipitatio...

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Detalles Bibliográficos
Autores principales: Bish, Rebecca, Cuevas-Polo, Nerea, Cheng, Zhe, Hambardzumyan, Dolores, Munschauer, Mathias, Landthaler, Markus, Vogel, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598758/
https://www.ncbi.nlm.nih.gov/pubmed/26184334
http://dx.doi.org/10.3390/biom5031441