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Transcription Blockage Leads to New Beginnings

Environmental agents are constantly challenging cells by damaging DNA, leading to the blockage of transcription elongation. How do cells deal with transcription-blockage and how is transcription restarted after the blocking lesions are removed? Here we review the processes responsible for the remova...

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Detalles Bibliográficos
Autores principales: Andrade-Lima, Leonardo C., Veloso, Artur, Ljungman, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598766/
https://www.ncbi.nlm.nih.gov/pubmed/26197343
http://dx.doi.org/10.3390/biom5031600