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Direct and/or Indirect Roles for SUMO in Modulating Alpha-Synuclein Toxicity

α-Synuclein inclusion bodies are a pathological hallmark of several neurodegenerative diseases, including Parkinson’s disease, and contain aggregated α-synuclein and a variety of recruited factors, including protein chaperones, proteasome components, ubiquitin and the small ubiquitin-like modifier,...

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Detalles Bibliográficos
Autores principales: Vijayakumaran, Shamini, Wong, Mathew B., Antony, Helma, Pountney, Dean L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598771/
https://www.ncbi.nlm.nih.gov/pubmed/26213981
http://dx.doi.org/10.3390/biom5031697